摘要
建立了正相-高效液相色谱法测定拉坦前列素滴眼液中的有关物质,采用Zorbax Rx-SIL硅胶柱,以正己烷-无水乙醇(96︰4)为流动相,检测波长210 nm。拉坦前列素的最低检测限为8 ng。
A NP-HPLC method was established for the determination of the related substances in latanoprost eye drops. A Zorbax Rx-SIL column was used with the mobile phase of n-hexane-absolute ethylalcohol (96 " 4) at the detection wavelength of 210 nm. Its low limit of detection was 8 ng.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2013年第9期932-934,共3页
Chinese Journal of Pharmaceuticals