摘要
生物信息库对医学研究者是一个效用显著的资源,可也引起一系列伦理问题,如对其组织剩余物应采用何种类型知情同意;在没有获得捐赠者知情同意前提下,生物信息库研究是否可以展开、如何进行等;基于捐赠的伦理原则、捐赠者个人权利和社会共同利益的要求,本研究针对生物信息库在多大程度上进行知情同意,在特定情景下应采用哪种类型的知情同意等,提出样本及其数据处理2种可行选择,即对样本不可逆或可逆匿名化处理,同时对生物信息库建设中知情同意获取的必要性和合理性进行相关评估,以期为当前生物信息库研究的伦理实践提供参考。
The biobank for medical researchers is a resource of significant utility,which also causes a series of ethical issues.For example,the question of what kind of informed consent should be adopted for the biobanking tissue residue,whether related study can be conducted without the donors＇ consent and how to accomplish the biobank research.Based on ethical principles of donation,individual rights of donor and common interest of the society,this study suggested the informed consent that to which extent can be accepted for biobank and which type should be adopted in different scenes with two feasible choices.One is the irreversible,and the other is the reversible anonymization process for samples.The necessity and rationality of informed consent for biobank con struction were also evaluated in order to provide references for the ethical practice of biobank research.
出处
《世界科学技术-中医药现代化》
北大核心
2013年第4期729-734,共6页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
教育部博士点基金(20124425110004):基于P38MAPK信号通路的间充质干细胞对骨关节炎免疫调节机制及补肾活血中药干预研究
负责人:刘军
