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高致病性禽流感H5N1病毒基因改造引发争议案例剖析 被引量：7

Case analysis of controversy caused by genetically engineered highly pathogenic H5N1 virus
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摘要 高致病性禽流感(HPAI)H5N1病毒基因改造研究及美国国家生物安全科学咨询委员会(NSABB)的监管建议引起广泛争议。旨在通过对HPAI H5N1病毒基因改造及监管相关信息的分析,探讨有关两用性研究发展和监管的趋势。通过研究,梳理并总结出三大核心争议问题:禽流感H5N1病毒基因改造风险、实验室生物安全等级及研究论文是否应该全文公开发表。 Over the past months,numerous articles and opinions have focused on genetically engineered highly pathogenic H5N1 virus and the oversight recommendations of the National Science Advisory Board for Biosecurity（NSABB） in the USA.The article is to discuss the future and oversight of dual-use of research concerns by analyzing the articles and opinions.Case analysis focuses on three major problems： benefits and risks of research,biocontainment levels for research,and whether the manuscripts should be published.
作者 董时军 刁天喜
机构地区 军事医学科学院卫生勤务与医学情报研究所 解放军第
出处 《军事医学》 CAS CSCD 北大核心 2013年第8期635-638,共4页 Military Medical Sciences
关键词 禽流感 流感病毒A型 H5N1亚型 基因工程 案例分析 生物安全 生物安保 avian influenza influenza A virus H5N1 subtype genetic engineering case analysis biosafety biosecurity
分类号 R373 [医药卫生—病原生物学]
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参考文献28

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同被引文献79

  • 1刘崇海,蒋利萍,魏钰书.流感病毒感染动物模型的研究进展[J].国际病毒学杂志,2006,13(1):9-12. 被引量：18
  • 2NSABB. United States Government Policy for Oversight of Life Science Dual Use Resarch of Concern[EB/OL]. http://oba.od.nih. gov/oba/biosecurity/PDF/United_States Government Policy_for_ Oversight of_DURC_FINAL_version_032812.pdf. 2013-01-11.
  • 3OSTP. United States Government Policy for Institutional Over- sight of Life Sciences Dual Use Research of Concern[EB/OL]. http: //www.phe.gov/s3/dualuse/Documents/oversight- durc.pdf. 2013- 04-26.
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  • 7NSABB. National Science Advisory Board for Biosecurity Find- ings and Recommendations March 29-30, 2012[EB/OL]. http:// oba.od.nih.gov/oba/biosecurity/PDF/03302012_NSAB B_Recomme- ndations.pdf. 2013-06-10.
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  • 9Frankel M S. Regulating the boundaries of dual-use research [J]. Science, 2012,336(6088):1523-1525.
  • 10Malakoff D. U.S. agencies to start screening biomedical propos- als for dual use[J]. Science, 2012,336(6077):21.

引证文献7

二级引证文献44

军事医学
2013年 第8期

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