球囊扩张椎体后凸成形术治疗骨质疏松性椎体压缩骨折的疗效观察

Clinical Effect of Percutaneous Kyphoplasty in Treatment of Osteoporotic Vertebral Compressive Fracture

目的观察球囊扩张椎体后凸成形术治疗骨质疏松性椎体压缩骨折的临床疗效。方法将2010年4月至2012年11月收治的80例骨质疏松性椎体压缩骨折患者,随机分为实验组(n=40)和对照组(n=40),实验组采用球囊扩张椎体后凸成形术治疗,对照组采用经皮椎体成形术治疗。结果所有患者术后随访6个月。两组患者术后VAS评分、Cobb's角和ODI评分均显著小于术前(P<0.05),实验组术后6个月VAS评分显著小于对照组(P<0.05),实验组术后3d和术后6个月的Cobb's角和ODI评分均显著小于对照组(P<0.05),实验组骨水泥渗漏率显著低于对照组(P<0.05)。结论球囊扩张椎体后凸成形术治疗骨质疏松性椎体压缩骨折疗效确切,安全性好,可以作为治疗骨质疏松性椎体压缩骨折的首选方法之一。

Objective To explore the clinical effect of percutaneous kyphoplasty in treatment of osteoporotic vertebral compressive fracture. Methods From April 2010 to November 2012, 80 patients with osteoporotic vertebral compressive fracture were randomly divided into 2 groups, experimental group （n=40） and control group （n=40）. Patients in experimental group were treated with percutaneous kyphoplasty, while patients in control group were treated with percutaneous vertebro-plasty. Results All the patients were followed up for 6 months. The VAS score, Cobb＇s angle, and ODI score after operation were significantly lower than those before operation in both two groups （P〈0.05）. The VAS score in experimental group was significantly lower than that in control group 6 months after operation （P〈0.05）. Furthermore, the Cobb＇s angle and ODI score in experimental group were significantly lower than those in control group 3 days and 6 months after operation （ P〈0.05）. In addition, the leakage rate of bone cement in experimental group was significantly lower than that in control group after operation （P〈0.05）. Conclusion Percutaneous kyphoplasty in treatment of osteoporotic vertebral compressive fracture is effective and reliable. It can be the preferred method in treatment of osteoporotic vertebral compressive fracture.