阿奇霉素联合痰热清在支气管扩张症急性期治疗中的疗效观察

Clinical efficacy of azithromycin combined with Tanreqing for the therapy of acute bronchiectasis

目的探究阿奇霉素联合痰热清在支气管扩张症治疗中的疗效。方法选择2009年1月至2011年12月确诊为支气管扩张症而就诊的112例患者。随机分为观察组56例和对照组56例。观察组给予阿奇霉素0.5g加入5%葡萄糖注射液250mL;痰热清注射液20mL加入5%葡萄糖注射液250mL静脉用药,每日1次。对照组给予左氧氟沙星0.4g加入5%葡萄糖注射液250mL;盐酸氨溴索30mg加入生理盐水100mL静脉用药,每日1次。结果观察组在症状改善、咳嗽、发热、肺部症状上比对照组有着更好的临床疗效,两组的治愈率比较差异有统计学意义(P<0.05)。结论阿奇霉素联合痰热清在支气管扩张症的治疗中疗效明显。

Objective To explore the clinical efficacy of azithromycin combined with Tanreqing for the therapy of acute bronchiectasis.Methods From January 2009 to December 2011,112 patients with bronchiectasis in the Third Affiliated Hospital of Guangxi Medical University were reviewed and devided into observation group and control group,56 patients in each group.Observation group was treated with azithromycin 0.5 g which was added in 5% glucose injection 250 mL combined with Tanreqing 20 mL which was added in 5% glucose injection 250 mL,QD.Control group was treated with levofloxacin 0.4 g which was added in 5% glucose injection 250 mL combined with ambroxol hydrochloride 30 mg which was added in physiological saline 100 mL,QD.Results Observation group in improving symptoms,cough,fever,pulmonary symptoms was better than the control group,there was statistical significant difference（P0.05）.Conclusion Azithromycin combined with Tanreqing has got obvious effect in the treatment of bronchiectasis.