急性白血病合并感染66例临床观察

The Clinical Observation of 66 Cases of Acute Leukemia

目的:总结掌握急性白血病合并感染的临床特点。方法:通过对本院收治的66例并发感染的急性白血病患者的临床特点进行总结归纳,从患者感染率、致病因素、致病菌等多个方面进行分析。结果:急性白血病患者的感染率达到92.4%,其中革兰氏阴性杆菌导致感染的比例为47.5%,革兰氏阳性球菌导致感染的比例为41%,真菌导致感染的比例为11.5%。患者容易出现感染的部位为上呼吸道、肺部及口腔。本文通过临床调查发现,感染的因素往往同患者年龄、相关治疗及病原体等因素有着直接的关系,此外患者骨髓增生的程度及粒细胞的数目同样对感染有着重要的影响。结论:急性白血病患者属于易出现感染的高危人群,应充分引起注意。

Objective： To summarize the master of acute leukemia c｜inical features of infection.Method： The patient infection rates, risk factors, pathogens, and other aspects of 66 cases of concurrent infections in patients with acute leukemia were analyzed.Result： The leukemia infection rate of patients was 92.4 percent, of which the proportion of gram-negative bacteria cause infection was 47.5%, gram-positive cocci cause infection ratio of 41%, the proportion of fungal infection resulted 11.5% ; patients prone the site of infection to the upper respiratory tract, lung and oral cavity. This discovery through clinical investigation, infection factors were often the same age, and other factors related to treatment and pathogens had a direct relationship, in addition to the degree of bone marrow hyperplasia and the number of granulocytes also had an important impact on the infection. Conclusion： Acute leukemia patients are prone to infection in high-risk groups should be fully attention.