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布比卡因脊麻联合氯胺酮复合丙泊酚静脉麻醉在成骨不全患儿下肢手术中的应用 被引量:2

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摘要 目的观察布比卡因脊麻联合氯胺酮复合丙泊酚静脉麻醉用于成骨不全患儿下肢手术的安全性和有效性。方法选择成骨不全单侧下肢截骨矫形患儿40例,随机分为B、Q组各20例。B组给予0.5%布比卡因脊麻联合氯胺酮复合丙泊酚静脉麻醉,Q组给予瑞芬太尼、丙泊酚、罗库溴铵气管插管诱导全身麻醉,瑞芬太尼复合丙泊酚静脉泵注维持。记录麻醉前、麻醉后0.5 h、截骨后、术毕患儿的MAP、HR、SpO2,观察不良反应发生情况。结果两组均顺利完成手术。B组截骨后MAP高于Q组(P<0.05);术毕HR低于Q组(P<0.05);B组麻醉后0.5h、截骨后SpO2低于Q组,术毕SpO2高于Q组,P均<0.05。两组术中、术后均无呼吸抑制、喉痉挛、高热,术毕6 h后均无嗜睡,不良反应发生情况无统计学差异。结论 0.5%布比卡因脊麻联合氯胺酮复合丙泊酚静脉麻醉可用于成骨不全患儿下肢手术麻醉,且对血流动力学影响小。
出处 《山东医药》 CAS 2013年第32期63-65,共3页 Shandong Medical Journal
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