当飞利肝宁胶囊联合生活干预治疗非酒精性脂肪肝的疗效观察

Therapeutic Effect of Dang-Fei-Li-Gan-Ning Capsule Combined with Lifestyle Intervention in Treatment of Non-alcoholic Fatty Liver Disease

目的:探讨当飞利肝宁胶囊联合生活干预治疗非酒精性脂肪肝(NAFLD)疗效。方法:将120例非酒精性脂肪肝患者分为治疗组和对照组,治疗组采用当飞利肝宁胶囊加生活干预治疗,对照组只使用当飞利肝宁胶囊治疗,比较两组患者的治疗效果。结果:治疗组的总有效率为90.0%,显著高于对照组的56.7%(P<0.01)。治疗组治疗后的ALT、AST、TG、TC、LDL、BMI及肝脏影像学的改善显著优于对照组(P<0.01)。结论:当飞利肝宁胶囊联合生活干预对非酒精性脂肪肝有显著改善,值得临床推广。

Objective： To investigate the effect of Dang-fei-li-gan-ning capsule combined with lifestyle intervention in the treat- ment of non-alcoholic fatty liver disease （NAFLD）. Methods： 120 patients with non-alcoholic fatty liver were divided into treatment group and control group, the treatment group was treated with Dang-fei-li-gan-ning capsule combined with lifestyle intervention, the control group only used the Dang-fei-li-gan-ning capsule, the therapeutic effects of the two groups were compared. Results： The total effective rate in the treatment group was 90%, significantly higher than 56. 7% in the control group （ P 〈 0. 01 ）. After treatment, the improvements of ALT, AST, TG, TC, LDL, BMI and liver imaging were significantly better in the treatment group than the con- trol group （P 〈 0. O1 ）, Conclusion： Dang-fei-li-gan-ning capsule combined with lifestyle intervention has significant improvement on non-alcoholic fatty liver disease, was worthy of promotion in clinical practice.