组织多普勒成像技术对甲状腺疾病患者右室功能的评价价值

Evaluation on right ventricular function of patients with thyroid dysfunction by tissue Doppler imaging

目的:探讨应用组织多普勒成像(TDI)技术评价甲状腺疾病患者右室功能的价值。方法:选取30例甲状腺功能亢进(甲亢)患者,30例甲状腺功能低下(甲低)患者,另选取30例各项检查正常者为对照。TDI模式下,将取样容积置于患者心尖四腔心切面右室侧壁三尖瓣前叶及隔叶瓣环附着处,测量心肌收缩期峰值速度(Sa)、舒张早期峰值速度(Ea)、舒张晚期峰值速度(Aa)、等容收缩时间(ICT)、射血时间(ET)、等容舒张时间(IRT),并计算Ea/Aa和右室Tei指数。结果:①3组右室侧壁Sa、Ea、Aa、Ea/Aa、ICT、IRT及右室Tei指数差异均有统计学意义(F=61.050、35.021、29.797、272.981、9.301、40.800和81.141,P均<0.05)。与对照组比较,甲亢组Sa、Aa增大,Ea/Aa、ICT减小,Tei指数增大(P均<0.05);甲低组Tei指数、IRT增大,Ea、Ea/Aa减小(P均<0.05)。②3组右室间隔壁Sa、ICT、IRT及右室Tei指数差异有统计学意义(F=55.968、18.489、34.466和29.597,P均<0.05)。与对照组比较,甲亢组Sa、Tei指数增大,ICT减小(P均<0.05);甲低组Tei指数、IRT增大(P均<0.05)。结论:TDI参数可以较好地反映甲状腺疾病患者右室功能。

Aim：To explore the value of tissue Doppler imaging （ TDI） for the right ventricular function evaluation of patients with thyroid dysfunction .Methods：Thirty patients diagnosed with overt hypothyroidism ,30 with hyperthyroidism and 30 healthy subjects were included in the study .The frequency spectrogram of tricuspid annular motion was obtained by TDI.The peak systolic velocity （Sa）, the peak velocity at early diastole （Ea） and at late diastole （Aa）, isovolumetric contraction time（ICT）,ejection time（ET）, isovolumetric relaxation time （IRT） were detected, and Ea/Aa and right ven-tricular Tei index were calculated .Results：There were significant differences in Sa ,Ea,Aa,Ea/Aa,ICT,IRT and Tei in-dex of lateral wall among the 3 groups（F=61.050,35.021,29.797,272.981,9.301,40.800 and 81.141, all P〈0.05）. Compared with those of the control group ,Sa,Aa and Tei index in hyperthyroidism group were higher , Ea/Aa, ICT were lower（P〈0.05）;while IRT and Tei index were higher,and Ea, Ea/Aa were lower in hypothyroidism group（P〈0.05）. The differences in Sa,ICT,IRT and Tei index of septal wall among the 3 groups were significant （F=55.968,18.489, 34.466and 29.597, all P〈0.05）.Compared with those of the control group , Sa and Tei index in hyperthyroidism group were higher, ICT were lower（P〈0.05）;while IRT and Tei index were higher in hypothyroidism group （P〈0.05）.Con-clusion：TDI parameters could accurately and directly reflect the right ventricular function of patients with thyroid dysfunc -tion.