降钙素原、CRP联合Balthazar分级对急性胰腺炎患者临床风险预测的意义

Prognostic clinical risk significance of serum poralcitonin and CRP level joint epigastrium Balthazar computed tomography in patients with acute pancreatitis

目的评估血清中降钙素原、CRP水平联合上腹部Balthazar分级对急性胰腺炎(AP)患者临床风险预测的意义。方法检测52例轻症AP(MAP)组和27例重症AP(SAP)组及17例对照组血清降钙素原、CRP水平、联合Balthazar分级,并动态观察以上各指标在入院时、入院72 h的变化。结果降钙素原、CRP联合上腹部联合Balthazar分级有高度的敏感性,治疗前后比较差异有统计学意义(P<0.05),MAP组与SAP组降钙素原、CRP、Balthazar分级比较差异有统计学意义;对照组在治疗前后变化不明显(P>0.05)。结论对AP患者采取动态监测血清降钙素原、CRP联合Balthazar分级对患者的临床分型风险预测、转归愈合具有较重要的临床意义。

Objective Evaluation of serum poralcitonin （PCT） and C-reactive protein （CRP） level joint epigastrium Balthazar grade of acute pancreatitis patients clinical risk prediction significance. Methods Fifty two cases of mild acute pancreatitis and 27 cases of severe acute pancreatitis, 17 cases of controls were tested by serum PCT and CRP level, Balthazar grade, and dynamic observation of the above indicators on ad- mission, 72 h changes. Reuslts PCT and CRP joint epigastrium Bahhazar grade has a high degree of sensitiv- ity, there were significant differences in before and after treatment （ P 〈 O. 05 ） , mild acute pancreatitis and se- vere acute pancreatitis between PCT, CRP, Balthazar grade also have significant difference; control group be- fore and after treatment does not change significantly （ P 〉 0. 05 ）. Conclusions For the patients of pancreatitis take dynamic monitoring serum PCT and CRP joint Bahhazar grade in patients with acute pancreatitis clinical parting risk prediction, outcome healing have an important clinical significance.