调节血脂治疗的药学监护

Pharmaceutical Care in Medication for Blood Lipid Regulation

目的 :科学合理地应用调节血脂药,不仅可降低血脂水平,还可减少血管内皮过氧化,稳定或缩小动脉粥样硬化脂质斑块,减少脑卒中和心血管事件的发生,成为一、二级预防心血管病的重要手段,本文对调节血脂治疗中的药学监护要点进行总结。方法:查阅近年来国内、外相关文献,对调节血脂药的研究进展进行分析。结果:联合治疗方案对血脂达标和治疗成败非常关键,使得药学监护十分重要。结论:调节血脂药的合理和安全应用尤为重要,应监护其在治疗中的各种风险和问题,诸如调节血脂药选择、联合用药方案、不良事件(肌毒性、肝毒性)的防范等,并依据血脂类型选择适宜的给药时间。

Objective：The application of lipid regulating agents scientifically and rationally can lower the blood lipid level , reduce the oxidative damage to vascular endothelial cell , stabilize or decrease atherosclerotic plaques and reduce the incidence of stroke and cardiovascular events , which has been regarded as an important means for the primary and secondary prevention . This paper summarized the critical points of pharmaceutical care in regulating blood lipid therapy . Methods：Through reviewing the pertinent medical literatures both at home and abroad published in recent years , a analysis was performed of the research progress on lipid regulating drugs . Results：The combined treatement scheme was crucial to the blood lipid level and the result of treatment , and the great importance of pharmaceutical care was thusly proved . Conclusion： It is of great importance to use lipid regulating drugs in a rational and safety way . Attention should be paid to the risk and problem in the treatment , such as the selection of lipid regulating drugs , combined treatment scheme of medication and the prevention of adverse drug events （ muscle toxicity and hepatotoxicity ） , and a suitable time of administration should be chosen according to the lipid types .