抗菌肽对断奶仔猪生产性能和健康水平的影响

Effects of Antimicrobial Peptide on Growth Performance and Health of Weaning Piglets

为了探讨抗菌肽对断奶仔猪生产性能和健康水平的影响，选取144头（25±3）日龄、体质量相近[（6．91±1．10）kg]的杜×长×大三元杂交断奶仔猪，随机分成3组，即基础日粮组（对照组）、基础日粮＋0．2％抗菌肽组（试验1组）和基础日粮＋0．4％抗菌肽组（试验2组），试验周期28d，测定其生产性能和血清相关指标的变化。结果显示，与对照组相比，试验前期（1～14d）试验2组仔猪平均日增体质量、平均日采食量和料重比分别提高11．3％、3．8％和6．4％，但组间差异不显著。试验1组和试验2组死淘率显著降低，试验2组的血清IgG和血清总胆固醇显著高于对照组、尿素氮显著低于其他组。另外，试验1组和试验2组血清丙二醛含量显著低于对照组，试验2组的抗氧化能力显著高于对照组和试验1组。表明抗菌肽能显著改善断奶仔猪的生产性能，提高血清IgG水平、抗氧化性能和健康水平，降低死淘率。

In order to study the effect of antimicrobial peptide on growth performance and health of weaning piglets,144 weaning piglets[（25 ± 3） d of age, Landrace × Yorkshire × Duroc, initial body weight： （6.91±1.10）kg] were randomly allotted to 3 treatments. There were 3 replicate pens in each treatment with 16 pigs per pen. The dietary treatments were basal diet （control）, basal diet ＋ 0. 2% antimierobial peptide （group 1） and basal diet ＋ 0. 4 % antimicrobial peptide （group 2）. The experimental diets were fed in for 2 phases（I-14 d,prior phase and 15--28 d,la- ter phase post-weaning）. The growth performance and serum related indices of 3 treatments were measured. The results showed that ADG,ADFI and F/G of the piglets in group 2 were increased by 11.3% ,3.8% and 6.4% ,but difference between the group 2 and control was not significant. The death and culling rates of the piglets in group 1 and group 2 were significantly lower than that of control,the serum IgG and TC content of group 2 were significantly higher,and the serum BUN level was significantly lower than that of group 1 and control. In addition,the serum MDA content in group 1 and 2 was significantly lower than that of control, and the serum T-AOC activi- ty in group 2 was significantly higher than that of goups 1 and control. It can be inferred that the serum IgG level,antioxidant capacity and health of the weaning piglets could be significantly im- proved with antimicrobial peptide supplementation in the diets,and the death and culling rate re- duced as well.