高龄胃癌患者根治术疗效的影响因素

Factors Influencing the Efficacy of Gastrectomy for Elderly Gastric Cancer Patients

目的探讨影响高龄胃癌患者根治术疗效的相关因素。方法 126例老年胃癌患者分为远端胃切除胃癌根治术组(58例)和近端胃切除胃癌根治术组(68例)。比较两组患者术中、术后恢复情况以及术后生存率,并对术后生存率的影响因素进行分析。结果远端胃切除胃癌根治术组和近端胃切除胃癌根治术组相比,手术时间和术中出血量等无明显差异,肿瘤未侵犯血管的患者术后生存时间远长于肿瘤侵犯血管者。不同化疗方案对患者术后生存时间的影响也非常显著。结论影响高龄胃癌患者的独立性因素分别为患者年龄,肿瘤大小,肿瘤浸润深度,术后化疗方案及淋巴结转移。

Objective To investigate the factors influencing the efficacy of gastrectomy for elderly gastric cancer pa- tients. Methods 126 elderly patients with gastric cancer were divided into the distal gastrectomy group with 58 cases and the proximate gastrectomy group with 68 cases. The intraoperative and postoperative recovery, survival rates of the 2 groups were com- pared, and the factors influencing postoperative survival rates were analyzed. Results The operation time and the bleeding vol- ume of the 2 groups had no significant difference, the postoperative survival time of the patients without malignancies with involve- ment of major vessels was higher than that of the patients with malignancies with involvement of major vessels. The different chem- otherapy regimens had great difference in the postoperative survival time of the patients. Conclusion The independent factors in- fluencing the survival of elderly patients are age, tumor size, depth of invasion, chemotherapy and lymph node metastasis.