短暂性脑缺血发作与颅内、外动脉狭窄之间的关系探讨

The Relationship between transient ischemic attack (TIA) and cerebral arterial stenosis

目的探讨短暂性脑缺血发作(TIA)与颅内、外动脉狭窄的发生率、分布特征、狭窄程度以及与侧支循环之间的关系。方法 107例TIA患者均进行DSA检查,明确有无颅内、外动脉狭窄及其狭窄的部位和程度,并判断有无侧支循环的建立。结果 93例DSA阳性患者存在颅内、外动脉狭窄和闭塞共计156处。颅内动脉狭窄最多见于大脑中动脉,共46处(29.5%),颅外动脉狭窄病变多见于颈内动脉开口处,共22处(14.1%)。重度狭窄及闭塞组侧支循环发生率明显高于轻度、中度狭窄组。结论颅内、外动脉狭窄是TIA发病的重要基础,并且颅内动脉狭窄是较颅外动脉狭窄更为重要的TIA发病因素。

Objective To study the relationship between TIA and the incidence of intracranial and extracranial artery stenosis,the degree of stenosis,distribution characteristics as well as collateral circulation.Methods 107 cases were examined with digital subtraction angiography （DSA）.To clear existence of the cerebral vascular stenosis,the distribution of stenosis,and responsibility artery stenosis.Results 93 patients had cerebral arterial stenosis and occlusion in total 156 places.The intracranial lesion was most seen in total 46 places （29.5%） in the middle cerebral artery,the extracranial lesion was most seen at the opening of internal carotid artery in total 22 places （14.1%）.The incidence of collateral circulation in severe stenosis and occlusion group were significantly higher than that in mild and moderate group.Conclusion Intracranial and extracranial arterial stenosis are the important pathogenetic causes for TIA.Moreover,for TIA patients,the intracranial arterial stenosis is more important than the extracranial stenosis.