妊娠期分化型甲状腺癌的诊治进展

Progress of Diagnosis and Treatment for Differentiated Thyroid Carcinoma in Pregnancy

目的探讨妊娠期分化型甲状腺癌的诊治进展。方法复习妊娠期分化型甲状腺癌诊治的相关文献,进行回顾性分析和总结。结果妊娠期分化型甲状腺癌禁忌行核素扫描和放射性碘治疗,在妊娠中期行使手术相对安全,推迟到分娩后手术并不影响产妇的预后,但需在妊娠全程严密监测肿瘤的生长速度。结论妊娠期分化型甲状腺癌的诊治变得更复杂,其是内分泌科、外科及妇产科医生共同面临的挑战。

Objective To explore the progress of diagnosis and treatment for differentiated thyroid carcinoma （DTC） in pregnancy. Methods The literatures on studying the diagnosis and treatment of DTC in pregnancy were reviewed and analyzed retrospectively. Results Radionuclide scanning and radioiodine （131I） administration during pregnancy were contraindicated. Surgery during the second trimester was considered safe. Monitoring of pregnancy must be strict during each trimester if surgery was delayed until after delivery. Conclusions Pregnancy makes the diagnosis and treatment of DTC become more complicated, the diagnosis and treatment of DTC during pregnancy present a challenging situation for the endocrinologists, surgeon, and obstetrician.