正性肌力药物在收缩性心力衰竭中的临床应用进展

Progress on the treatment of children＇s systolic heart failure by positive inotropic drugs

儿童心力衰竭是一种儿科常见危重症。收缩性心力衰竭可由先天性心脏病、暴发性心肌炎、心律失常性心肌病等儿科常见心血管疾病引起。正性肌力药物是临床中治疗收缩性心力衰竭的常用药物，包括洋地黄类药物、β-受体激动剂、磷酸二酯酶抑制剂及钙增敏剂4种。本文将对各类正性肌力药物的应用及进展进行探讨。

Heart failure is a common critical disease in children. Systolic heart failure can be caused by common diseases in children such as congenital heart disease, fulminant myocarditis and arrhythmogenic cardiomyopathy. Positive inotropic drug is the most common medication for treating systolic heart failure in children. Common inotropic drug includes digitalis, β-receptor agonist, phosphodiesterase inhibitor and calci- um sensitizers. This article reviewed the using and progress of positive inotopic drugs.