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儿童重症肺炎与胃食管反流关系的临床研究 被引量:5

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摘要 目的了解重症肺炎患儿胃食管反流( gastroesophageal reflux, GER)的发生及其影响因素。方法对2009年2月至2011年2月于我科PICU就诊的确诊为重症肺炎患儿25例(肺炎组)和正常儿童10例(对照组)进行连续食管pH监测,监测时间包括鼻饲前1h和餐后3h。结果肺炎组GER发生率为60.0%(15/25),对照组GER发生率为20.0%(2/10),两组比较差异有统计学意义(χ2=4.58,P〈0.05)。肺炎组GER84.5%出现于咳嗽/吸痰和腹部压力增加时。肺炎组与对照组各项反流指标比较差异均有统计学意义(P均〈0.05)。重症肺炎患儿中伴GER者高血糖、腹胀、脓毒症、使用糖皮质激素的发生率明显高于不伴GER者(P均〈0.05)。结论重症肺炎儿童GER发病率高,表现为酸反流次数增加,酸清除能力降低。GER发生与疾病的严重程度相关。
出处 《中国小儿急救医学》 CAS 2013年第5期530-532,共3页 Chinese Pediatric Emergency Medicine
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参考文献12

  • 1Nind G, Chen WH, Protheroe R, et al. Mechanism of gastroe- sophageal reflux in critically ill mechanically ventilation pa- tients. Gastroenterology,2005,128 ( 3 ) :600-606.
  • 2Srivastava R, Downey EC, O'Gorman M, et al, Impact of fundo- plication versus gastrojejunal feeding tubes on mortality and in preventing aspiration pneumonia in young children with neuro- logic impairment who have gastroesophageal reflux disease. Ped- iatrics,2009,123( 1 ) :338-345.
  • 3陆权.儿童社区获得性肺炎管理指南(试行)(上)[J].中华儿科杂志,2007,45(2):83-90. 被引量:603
  • 4杨明明,刘恩梅.儿童重症肺炎诊治进展[J].儿科药学杂志,2009,15(1):53-55. 被引量:20
  • 5蒋立虹,吴剑.前列腺素E_1在先天性心脏病合并肺动脉高压中的应用[J].中国临床药学杂志,2001,10(1):35-36. 被引量:34
  • 6Altman KW, Prufer N, Vaezi MF. The challenge of protocols for reflux disease:a review and development of a critical pathway. Otolaryngol Head Neck Surg,2011,145( 1 ) :7-14.
  • 7傅宏娜(综述),刘风林(审校).儿童胃食管反流病诊断治疗研究进展[J].国际儿科学杂志,2011,38(5):458-461. 被引量:3
  • 8Wang R,Yan X, Ma XQ, et al. Burden of gastroesophageal reflux disease in Shanghai,China. Dig Liver Dis,2009,41 (2) :110-115.
  • 9Ytiksel H, Yilmaz O, Kirmaz C, et al. Frequency of gastroesoph- ageal reflux disease in nonatopic children with asthma-like air- way disease. Respir Med, 2006,100 ( 3 ) :393-398.
  • 10Woodley FW, Mousa H. Acid gastroesophageal reflux reports in infants:a comparison of esophageal pH monitoring and multi- channel intraluminal impedance measurements. Dig Dis Sci, 2006,51 ( 11 ) :1910-1916.

二级参考文献45

  • 1陈爱斌.婴幼儿重症肺炎死亡高危因素分析[J].实用全科医学,2005,3(5):437-438. 被引量:21
  • 2中华医学会儿科学分会消化学组.全国首届小儿胃肠动力性疾病研讨会会议纪要[J].中华儿科杂志,2006,44(2):97-99. 被引量:8
  • 3袁壮,马沛然,邓力,方鹤松,卢競,江载芳,陈贤楠,陆权,张乾忠,张灵恩,范永琛,洪建国,胡仪吉,胡皓夫,赵祥文,赵顺英,耿荣,夏经,曹玲,鲁继荣,傅文永.50年来小儿肺炎诊治策略的变迁[J].中国实用儿科杂志,2006,21(12):881-908. 被引量:159
  • 4陆权.儿童社区获得性肺炎管理指南(试行)(上)[J].中华儿科杂志,2007,45(2):83-90. 被引量:603
  • 5乔俊英,栾斌.小儿重症肺炎的诊治策略[J].医学与哲学(B),2007,28(5):36-38. 被引量:31
  • 6Rudan I, Bosehi-Pinto C, Biloglav Z, et al. Epidemiology and etiology of ehildhood pneumonia [ J ]. Bull World Health Organ, 2008, 86(5) : 408-416.
  • 7Heffelfinger JD, Davis TE, Gebrian B, et al. Evaluation of children with recurrent pneumonia diagnosed by World Health Organization Criteria [ J]. Pediatr Infect Dis J, 2002, 21 (2) : 108-112.
  • 8British Thoracic Society of Standards of Care Committee. BTS guidelines for the community acquired pneumonia in childhood [J]. Thorax, 2002, 57(suppl) : S1-S24.
  • 9Cheong HF, Ger LP. Clinical application of the rapid pneumococcal urinary antigen test in the treatment of severe pneumonia in children [ J ]. J Microbiol Immunol Infect, 2008, 41(1): 41-47.
  • 10Basnet S, Adhikari RK. Hypoxemia in children with pneumonia and its clinical predictors [ J ]. Indian J Pediatr, 2006, 73(9) : 777-781.

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