孤立性纤维性肿瘤6例超声诊断及病理分析

The ultrasound diagnosis and pathologic analysis of solitary fibrous tumors in 6 cases

目的:探讨孤立性纤维性肿瘤(SFT)超声诊断学表现,对比其与病理学诊断的关系。方法:回顾性分析6例经手术病理证实的SFT超声诊断学表现,以及病理形态学和免疫表型。结果:6例中2例发生于盆腔,颈部、腹壁、颊部、颧部各1例。临床主要表现为相关部位的占位效应导致的非特异性临床症状。超声检查显示为低回声团块,彩色多普勒示其内部分可见血流信号。病理学改变显示呈梭形的瘤细胞,细胞稀疏区与细胞密集区共存。间质血管较丰富,部分呈扩张状。免疫组织化学染色CD34阳性,CD99阳性,Bcl-2阳性和Vimentin阳性。结论:有完整被膜的SFT常呈边界清晰的低回声团块。低阻力指数的血液动力学提示有恶性的倾向,可通过免疫组织化学确诊。

Objective：To explore the ultrasonic diagnostics features of solitary fibrous tumors （SFT） and their relationships with pathology. Methods ： The features of ultrasonic diagnostics, pathomorphology and immunophenotyping of 6 cases with SFT diagnosed by pathology were retrospectively analysed. Results： Two cases locating in pelvic cavity, 1 case locating in neck, 1 case locating in abdominal wall, 1 case locating in genal region and 1 case locating in zygomatic region were found. The major clinical manifestations were nonspecific clinical symptoms in lesions. The uhrasonography and color Doppler flow imaging showed hypoechoic area and blood flow sign in the inner of lesion. Fusiform tumor cell sparse area and concentration area and rich interstitial blood vessels with partial expanding were observed in pathology. The positive staining of CD34, CD99, Bel-2 and Vimentin were detected by immunohistochemistry. Conclusions：SFT with well-encapsulated tumor is the low echo conglomeration with clear boundaries. The low- resistance index of haemodynamics suggests that it maybe malignancy, which can be diagnosed by immunohistochemistry.