3Edward H,Shortliffe EH,James J.Biomedical Informatics:Computer Applications in Health Care and Biomedicine[M].(3rd edition).New York:Springer,2006.
4Drain PK, Primack A, Hunt DD, et al. Global health in medical education:a call for naore training and opportuni- ties[J]. Aead Med, 2007 (3) .. 226 - 230.
5Hsu SC, Ong GH. Evaluatien of problem-based learn- ing:a lecturer' S perspective[J]. Ann Acad Med Singa- pore,2001,30(5) ~524 - 527.
6World Health Organization. Global burden of disease (GBD) [ EB/OL]. [2013-04-05 ]. http://www, who. int/ healthinfo/global_burden disease/en/index, html.
7Collins FS. Reengineering translational science:the time is right[ J ]. Sci Transl Med ,2011,3 (90) :90cm17.
8Butler D. Translational research: crossing the valley of death [ J ]. Nature,2008,453 ( 7197 ) : 840-842.
9Sung NS, Crowley WF Jr, Genel M, et al. Central challen- ges facing the national clinical research enterprise [ J ]. JAMA,2003,289(10) : 1278-1287.
10Zerhouni E. Medicine. The NIH roadmap [ J ]. Science, 2003,302 ( 5642 ) :63-72.
6Lehmann CU, Altuwaijri MM, Li YC, et al.Translational research in medical irrformatics or from theory to practice.A call for an applied informatics joumal[J].Methods Inf Med, 2008,47 ( 1 ): 1-3.