依那普利联合氢氯噻嗪治疗高血压的临床疗效分析

Analysis of Clinical Efficacy of Enalapril and Hydrochlorothiazide in the Treatment of Hypertension

目的探讨依那普利联合氢氯噻嗪治疗高血压的临床疗效。方法 78例高血压患者,随机分为治疗组和对照组各39例,分别采用依那普利单药治疗和依那普利联合氢氯噻嗪治疗。结果治疗组的疗效(94.87%)大于对照组(87.18%),两组差异具有统计学意义(P<0.05);治疗组的不良反应率(5.13%)小于对照组(12.82%),两组差异具有统计学意义(P<0.05)。结论依那普利联合氢氯噻嗪治疗高血压的临床疗效显著且不良反应率低,适合原发性高血压的治疗,值得临床推广。

Oblective To investigate the clinical efficacy of enalapril and hydrochlorothiazide in the treatment of hypertension. Methods 78 cases of hypertensive patients, randomly divided into treatment group and control group with 39 cases in each group, respectively with enalapril monotherapy and enalapril plus hydrochlorothiazide treatment. Results The efficacy of the treatment group （94.87%） than that in the control group （87.18%）, the difference between the two groups was statistically significant （P〈0.05）; adverse reaction rates in the treatment group （5.13%） than the control group （12.82%）, the difference between the two groups was statistically significant （P〈0.05）. Conclusion Enalapril and hydrochlorothiazide in the treatment of hypertension clinical curative effect and the low rate of adverse reactions, treatment for hypertension, is worth the clinical promotion.