腹膜后局限性Castleman病(附3例报告)

Localized retroperitioneal Castleman′s disease:report of 3 cases

目的提高腹膜后局限性Castleman病的诊治水平。方法回顾性分析3例腹膜后局限性Castleman病患者的临床资料,并进行文献复习。其中男2例,女1例,发病年龄49~61岁,中位年龄56岁,肿瘤位于腹膜后,大小3.0cm×3.5cm×4.0cm^4.0cm×4.5cm×6.0cm。结果 3例患者肿瘤均经手术成功切除并经术后病理证实,临床分类均属于局限型。术后随访6~12个月,未见肿瘤复发。结论腹膜后Castleman病临床少见,可发生于淋巴组织的任何部位,术前CT检查对诊断该病有一定帮助,确诊有赖于病理学检查,手术切除为首选治疗方法 。

Objective To improve the diagnosis and treatment of localized retroperitioneal Castleman＇s disease. Methods 3 cases of localized retroperitioneal Castleman＇s disease were stud- ied retrospectively, there were 2 males and 1 female with a median age of 56 years old（range：49- 61）. The tumor located in retroperitioneal area,size from 3, 0 cm×3.5 cm×4.0 cm×4.0 cru×4.5 cm× 6.0 em,and the related literatures were reviewed. Results The retroperitionea lesions of the 3 cases were resected completely and confirmed as Castlemanrs disease by pathological examinations. And their clinical classifications were localized. The 3 cases were followed up for 6 to 12 months and no tumor recurrence was found. Conclusions Localized retroperitioneal CastlemanPs disease is rare, and it can occur anywhere lymphoid tissue is existing. Preoperative CT examination is helpful in the diagnosis of the disease, but its definite diagnosis depends on pathologic examinations. Surgi- cal resection of the lesions is the preferred treatment.