雷贝拉唑联用莫沙比利治疗慢性胃炎的临床疗效分析

Study the efficacy of Rabeprazole combined with Mosapride on chronic atrophic gastritis

目的探讨雷贝拉唑联合莫沙必利治疗慢性胃炎的临床治疗效果及应用价值。方法选择我院治疗的慢性萎缩性胃炎患者142例,随机分为观察组和对照组,对照组采用奥美拉唑联合阿莫西林、克拉霉素三联疗法进行治疗,观察组采用雷贝拉唑、莫沙必利联合阿莫西林、克拉霉素进行治疗,比较两组的临床治疗效果及幽门螺旋杆菌根治情况。结果观察组治疗效果优于对照组,经统计学分析,差异有统计学意义(P<0.05)。观察组幽门螺旋杆菌根除率高于对照组,经统计学分析,差异有统计学意义(P<0.05)。结论采用雷贝拉唑联用莫沙比利治疗慢性萎缩性胃炎疗效可靠,能够有效根除幽门螺旋杆菌,减轻患者的临床症状,值得在临床上大力推广使用。

Objective Discuss the effect of Rabeprazole combined with Mosapride on chronic atrophic gastritis the clinical therapeutic effect and application value. Methods Choose our hospital treatment of 142 cases of patients with chronic atrophic gastritis, randomly divided into observation group and control group, control group adopts the omeprazole combined with amoxicillin and clarithromycin triple therapy treatment, observation group with rabeprazole azole, Mosapride will combined with amoxicillin and clarithromyein treatment, observe the clinical therapeutic effect of two groups and the status of helicobacter pylori eradication. Result Observe the effect of treatment group is better than the control group, after statistics analysis, the difference was statistically significant （P〈0.05）. Observation group of helicobacter pylori eradication rate is higher than the control group, after statistics analysis, the difference was statistically significant （P〈0.05）. Conclusion Using Rabeprazole combined with Mosapride on chronic atrophic gastritis curative effect is reliable, can effectively eradicating helicobacter pylori, relieve the patient＇s clinical symptoms, is worth popularizing in clinical use.