类风湿关节炎合并肺间质纤维化的临床特征研究

Correlation with Clinical Index of Fibrosis in Patients with Rheumatoid Arthritis Complicated with Pulmonary

目的对类风湿关节炎合并肺间质纤维化患者的临床特征进行分析,为今后的临床诊治工作提供可靠的参考依据。方法选取2010年1月—2013年3月我院收治的类风湿性关节炎患者102例,按照是否合并肺间质纤维化分成合并组和单纯组,而后对这两组的临床观察指标进行对比分析。结果合并组患者的男性所占比例、吸烟者比例、患者年龄、发病年龄、抗环瓜氨酸抗体、类风湿因子、C反应蛋白水平以及骨破坏发生率均较单纯组高。结论类风湿关节炎患者合并肺间质纤维化可能与诸多临床指标均存在较大的相关性,临床应给予关注,采取有效措施进行预防和治疗。

Objective Correlation and clinical index of fibrosis in patients with rheumatoid arthritis complicated with pulmonary were analyzed,providing a reliable basis for clinical diagnosis and treatment of the future work.Methods In 2010 January —2013 year in March of rheumatoid arthritis patients treated 102 cases,according to whether with interstitial pulmonary fibrosis is divided into combined group and control group,then the clinical observation indexes of the two groups were compared.Results Of the two groups of patients with male proportion,the proportion of smokers,patient age,age of onset,anti-CCP antibodies,RF,CRP levels and bone destruction rate was higher than the simple group.Conclusion In patients with rheumatoid arthritis complicated with pulmonary interstitial fibrosis may have significant correlation with some clinical indexes,clinical should be given attention,to take effective measures for the prevention and treatment of.