我院76例患者中成药不良反应分析

Analysis of 76 Cases of Adverse Drug Reactions Induced by Traditional Chinese Medicine in Our Hospital

目的了解我院中成药不良反应(ADR)发生的规律和特点,为临床安全合理使用中成药提供参考。方法对2010—2012年收集的76例中成药ADR报告进行统计、分析。结果中药注射剂引起的ADR发生率居首位(76.3%),临床表现以皮肤及其附件损害最常见,其余涉及消化系统、心血管等系统等,品种以痰热清注射剂和热毒宁注射剂发生例数最多。结论使用中成药应严格遵守《中成药临床应用指导原则》,同时应加强和重视中药ADR监测工作,以减少和避免ADR的发生。

Objective To analyze the characteristics and regularities of the adverse drug reactions（ADR） of the Traditional Chinese Medicine（TCM） occurred in our Hospital and the clinical preparation for the rational use of medicine to provide more information.Methods 76 ADR induced by TCM collected in our Hospital from 2010 to 2012 were analyzed statistically.Results TCM injections caused by the incidence of ADR ranked first（76.3%）,Clinical manifestations in the skin and its appendages damage were the most common,the rest of the digestive system,cardiovascular system,The Tanreqing injections and Reduning injection occurred the largest number of cases.Conclusion Use of TCM should strictly abide by the ＂ guiding principles for clinical application of Chinese medicine＂,and great importance should be attached to TCM-induced ADR to reduce or avoid the occurrence of ADR.