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氟伐他汀治疗充血性心力衰竭的疗效观察 被引量:1

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摘要 目的观察氟伐他汀治疗充血性心力衰竭的临床疗效。方法选择充血性心力衰竭患者37例,按照随机数表分为对照组和治疗组。对照组给予常规抗心衰药物治疗,治疗组在上述治疗基础上加用氟伐他汀,观察治疗前和治疗后12周患者6min步行试验(6-MWT)、左心射血分数(LVEF)、B型脑利钠肽(BNP)、肿瘤坏死因子-a(TNF-α)水平。结果与治疗前比较,治疗后两组患者6-MWT和LVEF均显著升高,血清中BNP和TNF-α水平均显著降低;与对照组治疗后比较,治疗组治疗后6-MWT和LVEF较高,BNP和TNF-α水平较低,差异有统计学意义(P<0.05)。结论氟伐他汀可改善充血性心力衰竭患者的心功能,具有较好的临床疗效。
作者 宋显斌
出处 《临床合理用药杂志》 2013年第27期77-77,共1页 Chinese Journal of Clinical Rational Drug Use
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