左旋咪唑对马立克氏病疫苗接种鸡T淋巴细胞值的影响

EFFECT OF LEVAMISOLE ON T LYMPHOCYTE OF CHICKENS INOCULATED WITH MAREK'S DISEASE VACCINE

本试验采用 70只 1日龄雏鸡 ,随机分为试验组和对照组 (每组各 35只 )。两组雏鸡均肌肉接种马立克氏病疫苗 1只份。从疫苗接种的当日开始 ,在试验组雏鸡饲料内按每天每公斤体重 1 5mg计算 ,拌入盐酸左旋咪唑 ,连服三日 ;对照组雏鸡不服左旋咪唑。于接苗后的 1 5、2 5、35和 45天 ,从两组雏鸡中随机各取 1 0只 ,由翅静脉采血 ,做成血涂片 ,供检查T淋巴细胞用。试验结果 :于接苗后 1 5、2 5和 35天 ,试验组雏鸡T淋巴细胞的百分率平均值显著高于对照组 (p <0 .0 5 )。由此可见 ,雏鸡在接种马立克氏病疫苗的同时 ,服用左旋咪唑 ,可以促进T淋巴细胞的增殖 。

one-day chicks were randomly divided into experiment group and check group, with 35 for each. All chicks were inoculated with Marek's Diseaes (MD) vaccine routine dosage. At the meantime, only the experiment group was fed Levamisole hydrochloride 15mg/kg bodyweight/day for 3 , 15, 25,35 and 45 days after vaccination, 10 blood smears were randomly made from each group respsctively for T Lymphocyte test. The experiment result shows that 15, 25 and 35 days after vaccination, the average percentage of T Lymphocyte of experiment group was higher than the check group significantly (p<0.05). Thus feeding Levamisole can promote the proliferation of T Lymphocyte and Increase the cellular immunity in MD vaccination chickens.