细菌鞭毛马达——一种卓越的分子机器

Bacterial Flagellar Motor:A Splendid Molecular Motor.

鞭毛马达 (flagellarmotor)是一种分子旋转马达 ,它在细菌鞭毛的结构与功能中起着中心作用 .鞭毛马达的结构已基本清楚 ,主要由MotA、MotB、FliG、FliM和FliN 5种蛋白组成定子 (stator)和转子 (rotor) ,其驱动力来自于跨膜的H+或Na+流 .目前对鞭毛马达的旋转动力学及旋转力矩产生机制已有初步的了解 .鞭毛马达可作为研究分子旋转马达的理想模型 。

Flagellar motor is a molecular rotary motor,it plays central role on the structures and functions of bacterial flagella.The structure of flagellar motor was clarified on the whole,its stator and rotor were composed of five proteins:Mot A,Mot B,FliG,FliM and FliN.The driving force comes from transmembrane H + or Na + flux. At present its rotary dynamics and torque generating mechanisms were understood preliminarily.As a perfect research model for molecular rotary motor,the further study of flagellar motor would be very helpful for realizing the mechanisms of bioenergetic conversion and cell motility,thus its study is of widespread importance for biology.