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建立胎羊体外循环中的几个问题

Issues in Establishment of Fetal Lamb Cardiac Bypass
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摘要 利用胎羊体外循环模型观察胎盘功能及胎心功能变化 ,研究胎羊体外循环建立方法和存在问题。结果显示直接肺动脉插管较经右室流出道肺动脉插管出血少。表明胎羊保温、胎盘保护和防止术中出血及子宫收缩是实验成功的关键。 To study the placental and fetal heart function, cardiopulmonary bypass was established in fetal lambs and the different methods of cannulation were applied. The results showed that the direct pulmonary artery cannulating was more reliable than pulmonary artery cannulating through right ventricular outflow tract .Besides, the warming of the fetal lamb, avoiding of uterine contraction, umbilical cord twist and bleeding during operation should be also emphasized.
出处 《上海实验动物科学》 2000年第4期220-226,共7页 Shanghai Laboratory Animal Science
关键词 胎羊 体外循环 心脏手术 新生儿 Fetal lamb Cardiopulmonary bypass
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参考文献5

  • 1Allan LD, Crawford DC, Anderson RH, et al.Spectrum of congenital heart disease detected echocardiographically in prenatal life[J]. Br Heart J, 1985, 54:523-236.
  • 2Champsaur G, Parisot P, Martinot S, et al, Pulsatality improves hemodynamics during fetal bypass experimental comparative study of pulsatile versus steady flow[J], Circulation, 1994,90 (part2):Ⅱ-47-Ⅱ-50.
  • 3Reddy VM, McElhinney DB, Rajasinghe HA, et al. Role of the endothelium in placental dysfunction after fetal cardiac bypass[J]. J Thorac Cardiovasc Surg. 1999,17:343-351.
  • 4Turley K. Vlahakes GJ, Harrison MR, st al. Intrauterine cardiothoracic surgery: the fetal lamb model[J]. Ann Thorac Surg 1982:34(4):422-426.
  • 5Reddy VM, Liddicoat JR, Klein JR, et al. Fetal cardiac bypass using an in-line axial flow pump to minimize extracoporeal surface and avoid priming volume [J]. Ann Thorac Surg, 1996,62:393-400.

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