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肺炎克雷伯菌碳青霉烯酶流行及分子特征研究进展 被引量:4

Advances in epidemiology and molecular characterization of Klebsiella pneumoniae carbapenemase
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摘要 在各种介导肠杆菌科细菌对碳青霉烯类抗生素耐药的机制中,产肺炎克雷伯菌碳青霉烯酶(klebsiella pneumoniae carbapenemase,KPC)是最为常见的一种。KPC为A类β-内酰胺酶,编码基因通常位于质粒上,便于在细菌间传递。KPC主要分布在肺炎克雷伯菌中,也在大肠埃希菌、阴沟肠杆菌等常见肠杆菌科细菌中检出。本文就KPC的流行和分子特征进行综述。
出处 《解放军医学院学报》 CAS 2013年第10期1095-1097,共3页 Academic Journal of Chinese PLA Medical School
基金 首都发展与科学研究基金项目(2009-1023)~~
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