液基细胞学在恶性胸腔积液检查中的价值

Value of Liquid-based Cytologic Test (LCT) in malignant pleural fluids

目的:探讨液基细胞学检查方法在恶性胸腔积液中的诊断价值。方法:分别采用常规细胞学涂片及液基细胞学检查方法同时对100例恶性胸腔积液患者进行阳性检出率及组织学分型比较。结果:常规细胞学涂片阳性率为74%(74/100),液基细胞学检查阳性率为96%(96/100)。两种方法检出肿瘤均以腺癌最多见,其中常规细胞学为83.8%(62/74),液基细胞学86.4%(83/96),其余肿瘤类型均少见。结论:液基细胞学与常规细胞学涂片相比制片清晰,细胞形态保存较好,易于发现肿瘤。同时并可进行免疫细胞化学等方法辅助诊断,提高准确率。

Objective To evaluate the diagnosable value of Liquid - based Cytologic Test （ LCT ） in malignant pleural flu- ids. Method We compared the positive detectable rate and histology type through the conventional cervical smear and LCT for 100 patients with malignant pleural fluids. Results The positive rate of conventional cervical smear and LCT was 74% （74/100） and 96% （96/100） re speetively. The adenocarcinoma was the most detected one of these two methods, 83.8% （62/74）for conventional cervical smear, 86. 4% （83/96） for LCT, the other tumor types were rare. Conclusion Compared to the conventional cervical smear, the LCT is easy to find tumor, the preparation slides are clear and the cellular morphology preserve well. Meanwhile ,the immunoeytoehemical method could be applied as a auxiliary diagnosis. In this way, the aceuracy could be improved.