摘要
目的:建立灯盏细辛软胶囊的质量标准.方法:采用薄层色谱法对灯盏细辛软胶囊中野黄芩苷、1,3-O-二咖啡酰奎宁酸进行定性鉴别研究,并采用高效液相色谱法测定野黄芩苷的含量.结果:薄层色谱斑点清晰,阴性无干扰;含量测定测得野黄芩苷对照品进样量在0.053~2.120 μg范围内线性关系良好(r=0.999 8),平均加样回收率为100.30%,RSD为1.71%(n=6).结论:该方法简便、准确、可靠,可以有效控制灯盏细辛软胶囊的质量.
Objective: To establish the quality standard for Dengzhan Xixin soft capsules. Method : A TLC was used for the qualitative identification of scutellariu and 1,3-O-dicaffeoylquinic acid. An HPLC was used to determine the content of scutellarin. Result: The TLC spots were clear and well-separated without negative interference. The linear range of scutellarin was 0. 053-2. 120 p,g( r = 0. 999 8 ) with the average recovery of 100.30% ( RSD = 1.7 1% , n= 6). Conclusion : The method is simple, accurate and reliable. It can be used in the quality control of Dengzhan Xixin soft capsules.
出处
《中国药师》
CAS
2013年第9期1288-1289,1298,共3页
China Pharmacist
基金
国家药典委员会国家药品标准提高行动计划项目(编号:562)