摘要
目的:对辛伐他汀片中某一未知杂质进行定性分析。方法:用HPLC-MS对辛伐他汀片中一未知杂质进行定性分析。结果:根据HPLC-MS信息确定杂质结构。结论:该杂质为辛伐他汀酸乙酯。
Objective: To qualitatively analyze a certain unknown impurity in simvastatin tablets. Method: The structure of the unknown impurity was qualitatively analyzed by HPLC-MS. Result: The structure of the impurity was determined preliminarily by the information of HPLC-MS. Conclusion: The impurity is defined as simvastatin acid ester.
出处
《中国药师》
CAS
2013年第9期1357-1358,共2页
China Pharmacist
关键词
辛伐他汀片
未知杂质
定性分析
液质联用
Simvastatin tablets
Unknown impurity
Qualitative analysis
LC-MS