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三氮唑偶联的阿拉伯糖苷化白杨素衍生物的合成与表征 被引量：2

Synthesis and characterization of glycosylated chrysin derivative linked with 1,2,3-triazole
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摘要 利用点击化学,由三乙酰阿拉伯糖叠氮化物和炔丙基取代白杨素分子通过Cu催化的1,3-环加成反应得到了一种三氮唑阿拉伯糖苷化白杨素衍生物,利用核磁共振光谱、红外光谱、电子轰击质谱对其结构进行了表征,并利用元素分析测定了其组成.结果表明,所得合成产物为目标化合物. Based on ＂click chemistry＂, a glycosylated arabinoseyltriazole chrysin derivative was synthesized in good yield by way of the copper-mediated 1,3 dipolar cyctoaddition reaction of ti racetylarabinose azide and alkynyl-substituted chrysin. The structure of as-synthesized product was characterized by means of nuclear magnetic resonance spectrometry, infrared spectrome- try, and electron ionization-mass spectrometry, and its elemental composition was determined by elemental analysis. It was found that as synthesized product is the target compound.
作者 景临林 范小飞 马慧萍 樊鹏程 贾正平
机构地区 兰州军区兰州总医院药剂科 兰州大学药学院
出处 《化学研究》 CAS 2013年第5期466-469,共4页 Chemical Research
基金 国家自然科学基金(81202458)
关键词 白杨素 点击化学 糖基化三唑 合成 表征 chrysin click chemistry glycosyltriazole synthesis characterization
分类号 O629.9 [理学—有机化学]
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参考文献13

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二级参考文献51

共引文献41

同被引文献16

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化学研究
2013年 第5期

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