茜素红荷移光度法测定阿魏酸哌嗪

Spectrophotometric determination of piperazine ferulate based on the charge transfer reaction between piperazine ferulate and alizarin red

研究了茜素红与阿魏酸哌嗪的显色反应，建立了阿魏酸哌嗪含量测定的分光光度法．在水溶剂中阿魏酸哌嗪与茜素红发生荷移反应生成紫红色的复合物，其最大吸收波长为524nm，表观摩尔吸光系数为1．86×10^3L·mol^-1·cm^-1．阿魏酸哌嗪的浓度在1．60-48．0mg·L^-1范围内与体系的吸光度呈良好的线性关系，其线性回归方程为A=0．02107＋0．00393c（mg·L，R=0．9992），方法的检出限为1．19mg·L^-1将此新方法应用于阿魏酸哌嗪片中阿魏酸哌嗪含量的测定，回收率在97．5％～100．9％之间．

A new established using reaction between plex was formed. method for alizarin red piperazine f the determination of piperazine ferulate by spect as a chromogenic reagent. In water solution, erulate and alizarin red was investigated and th The apparent molar absorptivity of the comp at the maximum absorption wavelen 60--48.0 mg·L^-1 lofpiperazineferu was A = 0. 021 07＋0. 003 93 c （mg tionlimit was 1. 19 mg·L^-1. This ferulate in tablets with recoveries of gth of 524 nm. T late. The linear r ·L^-1） withacor new method is 97.5%0--100.9 he Beer＇s egresslon lex is 1.8 Law is ob equation relation coefficient rophotometry is charge transfer e purple color corn 6X10a L ·mol^-1 .cm-1 eyed in the range of 1. of the calibration curve of 0. 999 2. The detec- applied to the determination of piperazine