晚期胃底贲门癌介入治疗的临床研究

CLINICAL STUDY ON INTERVENTIONAL THERAPY IN ADVANCED GASTRIC CARDIA CANCER

目的:回顾性总结分析近10年选择性动脉化疗栓塞治疗晚期胃底贲门癌的技术与疗效。方法:182例晚期胃底贲门癌患者,采用介入技术选择性胃左动脉和腹主动脉灌注化疗和胃左动脉碘油乳剂栓塞或明胶海绵栓塞治疗,观察治疗效果并统计患者半年、1年和2年的生存率。结果:术后1个月临床症状改善率100%,142例(78.02%)胃底软组织肿块较术前缩小。182例患者半年、1年和2年的生存率分别为85.16%、64.84%和14.84%。结论:介入动脉化疗和栓塞能使肿瘤病灶坏死缩小,具有较好的治疗效果,可明显延长患者的生存期。

Objective：To retrospectively analyze the technology and curative effects of selective arterial embolism chemotherapy in treatment of advanced gaslric cardia cancer in recent 10 years. Methods：182 advanced gastric cardia cancer patients were treated wilh selective left gastric artery and abdominal aorta infusion chemotherapy, and left gastric artery iodine oil emulsion embolization or gelatin sponge embolizalion. The treatment effects and halfyear, 1-year, 2-year survival rate of all ltae patients were reecoredResulls：The clinical symploms improvement rate was 100% atfter （78.02%）1 monnth; the tumor of 142 cases （78.02%）reduced obviously compared that prior treatment The half year, 1-year, 2-year survival rate was respectively 85.16% 64.84%and 14.84%.Conclusions： Arterial embolism chemotherapy and embolizafion can make tumor necrosis and reducing~ so meathodhas better In^aanent effects on advanced gastric cardia cancer and can prolong survival time ofpatients.