我院眼科抗菌药物围术期预防使用分析与合理性评价

Analysis and Rational Evaluation of Perioperative Prophylactic Use of Antibacterial Drugs in Ophthalmology Department of Our Hospital

目的评价医院眼科围术期预防使用抗菌药物情况。方法随机抽取2012年1月至6月医院眼科出院手术病历114份,对其诊断、手术、抗菌药物局部用药、全身用药、用药时机、用药疗程等信息进行统计,对其用药合理性进行评价。结果围术期局部预防使用抗菌药物达100%,但存在用药时间过长问题,左氧氟沙星滴眼液(可乐必妥)和复方妥布霉素滴眼液(典必殊)术前术后交替应用多见。全身预防性应用抗菌药物比率过高,大都选用克林霉素磷酸酯针(福德)或头孢拉定针,以术中用药为主,部分病例用药疗程过长。结论眼科围术期预防使用抗菌药物以局部用药为主,辅以全身用药,但仍有一些问题亟待改进。

Objective To evaluate the prophylactic use of antibacterial drugs in the ophthalmology department of our hospital. Methods A hundred and fourteen discharged cases of ophthalmological surgery from January to June 2012 were randomly extracted and performed the statistical analysis on the information of diagnosis, operation, drug selection in topical/systemic administration of antibacterial drugs, administration time and treatment course for conducting the evaluation on the medication rationality. Results Topical prophylaxis use of antibacterial drugs reached to 100%, and the problem of excessive medication time existed. Another common phenomenon was the alter- nate application of Levofloxacin Eye Drops and Compound Tobramycin Eye Drops before and after operation. The systemic preventive application ratio of antibacterial drugs was too high, Clindamycin Phosphate Injection or Cefradine Injection was mostly selected, intraop- erative administration was dominant and the treatment course was too long in some cases. Conclusion Perioperative prophylactic use of antiscterial drugs in the ophthalmology department of our hospital is dominated by the local application and supplemented by the sys- temic medication, but there are still some problems needing to be further improved.