血液病患者不规则抗体检测分析

Blood patients with irregular antibodies test analysis

目的:分析不规则抗体在常见的血液病中分布特征,探讨对血液病患者输血前检测不规则抗体的价值。方法:用微柱凝胶方法对3 742例血液病患者输血前抗体筛查和鉴定,分析不规则抗体的类型和特征。结果:共检测出不规则抗体阳性患者98例(2.62%),其中同种抗体53例(54.1%),以抗-E抗体最多;自身抗体45例(45.9%),以IgG型抗体最多。在所有血液病患者中,自身免疫性溶血性贫血患者的不规则抗体阳性率居首位。结论:血液病患者的不规则抗体阳性率高于正常人群,对血液病患者输血前进行不规则抗体检测,有利于预防溶血性输血反应的发生,确保临床输血安全。

Objective： Analysis of the common blood in irregular antibodies in distribution characteristics, to study the value of irregular antibodies with blood patients pre-transfusion. Method： Using micr column gel test method, 3 742 blood staples were tested for antibody screening and identification. Analysis of the types and characteristics of irregular antibodies. Result： Ninety-eight cases were detected irregular antibodies, and the positive rate was 2.62%. Among them the same antibody 53 cases （54. 1%）,45 cases of auto antibodies（45.9%）. The most same antibody was anti E, IgG type antibody was most in auto antibodies. In all patients with blood,autoimmune hemol.ytic anemia patients＇s positive of irregular antibody was at the top. Conclusion The positive rate of irregular antibody with blood patients is higher than normal people, pre transfusion for irregular antibody test is benefit to prevent the occurrence of hemolytic transfusion reactions,ensure clinical transfusion safety.