口腔颌面部多间隙感染治疗效果观察

Clinical efficacy of treatment of oral and maxillofacial multiple space infections

目的探讨脓肿切开引流联合高压氧治疗口腔颌面部多间隙感染临床效果。方法选取2010年10月-2012年5月收治口腔颌面部多间隙感染患者120例,采用随机数字表法分为对照组和观察组,每组各60例,其中对照组患者采用常规对症治疗措施,观察组患者在对照组治疗基础上,采用脓肿切开引流联合高压氧治疗;比较两组患者临床治疗总有效率,治疗前后白细胞计数及并发症发生等。结果观察组患者临床治疗总有效率为96.7%,明显高于对照组的80.0%,差异有统计学意义(P<0.05);对照组与观察组患者治疗后白细胞计数分别为(6.15±0.75)×109/L,(2.49±0.34)×109/L,与治疗前白细胞计数相比均显著改善,且观察组患者改善程度明显优于对照组,差异有统计学意义(P<0.05);观察组患者并发症发生率为1.7%,明显低于对照组的11.7%,差异有统计学意义(P<0.05)。结论脓肿切开引流联合高压氧治疗口腔颌面部多间隙感染可有效控制感染,缓解临床症状,减少并发症发生风险,具有临床使用价值。

OBJECTIVE To investigate the theraPeutic effect of incision and drainage for abscess combined with hyperbaric oxygen on treatment of oral and maxillofacial multiple space infections. METHODS Totally 120 patients with oral and maxillofacial multiple space infections were chosen in the period from Oct 2010 to May 2012 in the hospital and randomly divided into two groups including control group （n= 60） with conventional symptomatic treatment and observation group （n^60） with incision and drainage for abscess combined with hyperbaric oxygen treatment on the basis of control group; and the total effective rate white blood cell count before and after the treatment and incidence of complication occurrence of both groups were compared. RESULTS The total effective rate of observation group （96.7 % ） was significantly higher than that of the control group （ 80.0 %）（P^0.05）. The white blood cell count of control the group was（6.15~0.75）109/L, the observation group （2.49-/-0. 34）109/ L,both were significantly improved as compared with that before the treatment and improvement degree of the observation group was significantly better than that of the control group （P ~ 0. 05）. And the incidence of complication of the observation group （1.70//00） was significantly lower than that of the control group （11.7%）（P d0.05）. CONCLUSION As used in the treatment of oral and maxillofacial multiple space infctions; incision and drainage for abscess combined with hyperbaric oxygen can efficiently control infections, relieve clinical symptoms, and reduce the risk of complication, and it is worthy of clinical application.