妊娠妇女合并急性肾盂肾炎的危险因素分析

Risk factors for acute pyelonephritis in pregnant women

目的探讨妊娠期合并急性肾盂肾炎患者的危险因素，以制定相应的干预措施。方法对2009年1月一2013年1月就诊的120例妊娠期合并急性肾盂肾炎产妇作为感染组，选择同期健康的360例孕妇作为非感染组，对比分析两组患者引起妊娠期合并急性肾盂肾炎的相关因素。结果120例感染组患者中段尿培养出大肠埃希菌81株占67．50％，其次为金黄色葡萄球菌占7．50％和肺炎克雷伯菌占6．67％；多因素logistic回归分析显示，贫血（OR=9．68，95％Cj：2．81～33．27）．高血糖（OR=8．41，95％CI：2．35～30．08）、妊娠中晚期（OR=7．85，95％CI：2．37~25．94）、妊娠左侧卧位（OR=0．23，95％CI：0．08～0．66）与妊娠期合并急性肾盂肾炎有着密切关系。结论贫血、高血糖、妊娠中晚、妊娠体位是妊娠期合并急性‘肾盂肾炎的独立危险因素。

OBJECTIVE To investigate risk factors of acute pyelonephritis in pregnant women and find the measures to prevent. METHODS During Jan 2009 to Jan 2013,120 cases as the infected group were retrospectively analyzed to find risk factors of acute pyelonephritis, meanwhile 360 healthy pregnant women were chosen as the non- infection group, then the risk factors for the acute pyelonephritis were obserued. RESULTS Urine culture results showed that Escherichia coli accounted for the highest proportion （57.50%） , followed by Staphylococcus aureus （7.50%） and Klebsiella pneumoniae （6.67%）. Andanemia（OR = 9. 68,95% CI： 2. 81 -- 33. 27）, hyperglycemia （OR= 8.41,95 %CI： 2.35-30.08）, middle and late pregnancy （OR= 7.85,95 %CI.. 2.37--25.94） and left lateral position （OR= O. 23,95 % CI： O. 08--0.66）were closely related to the acute pyelonephritis in the pregnant women. CONCLUSION The risk factors for acute pyelonephritis include andanemia, hyperglycemia, middle and late pregnancy, and left lateral position.