摘要
目的:分析0～3岁儿童血清25羟维生素D3〔25-(OH)D3〕水平,为科学合理地补充维生素D制剂提供理论依据。方法:随机抽取2010年3月～2011年10月于该院儿童保健门诊就诊的儿童1 462例,用ELISA法检测血清25-(OH)D3水平。结果:无锡市0～3岁儿童25-(OH)D3的平均水平为(79.92±22.97)nmol/L,男女童之间差异无统计学意义(P>0.05);早产儿25-(OH)D3水平为(69.63±26.9)nmol/L,明显低于非早产儿水平(80.3±22.74)nmol/L,差异有统计学意义(P<0.05);不同季节检测儿童25-(OH)D3水平之间差异有统计学意义(P<0.05),而在相同季节检测的6月龄和12月龄儿童25-(OH)D3水平差异无统计学意义(P>0.05);儿童25-(OH)D3水平出生后随着月龄而渐增加,至5月龄达最高峰,之后渐下降,不同年龄差异有统计学意义(P<0.01)。结论:无锡市0～3岁儿童血清25-(OH)D3水平较为适宜,早产儿25-(OH)D3水平低于非早产儿,0～3岁儿童25-(OH)D3水平自出生后随着月龄增加而增高,至5月龄达最高峰,之后渐下降。
Objective： To analyze the status of serum 25 - hydroxy vitamin in D3 （25 - （OH） D3 ] of children aged 0 - 3 years, so as to provide scientific evidence for vitamin D supplement. Methods ： 1 462 children who were 0 - 3 years old from department of the chil- dren health in our hospital from 2010. 3 - 2011.10 were collected, the levels of 25 - （OH） D3 in serum were determined by ELISA assays. Results： The average levels of 25 - （OH） D3 of children aged 0 -3 years were （79. 92 ±22. 97） nmoL/L in Wuxi, there were no statistics difference between male and female （P 〉 0. 05 ） ; the contents of 25 - （OH） D3 in premature infant [ （69. 63 ±26. 9） nmol/L] were lower than no premature [ （80. 3 ±22.74 ） nmol/L] , and there were significant difference （P 〈0. 05） ; there were significant differ- ence of content of 25 - （OH） D3 between different seasons （ P 〈 0. 05 ） , however, there were no statistics difference between 6 months and 12months children in the same season detecting; the levels of 25 - （OH） D3 were increased by age, then decreased by age after at the peaks on 5 months, there were statistics difference of 25 - （OH） D3 levels between different age （P 〈 0.01 ） . Conclusion： The levels of 25 - （OH） D3 in serum are better in Wuxi, and the levels of 25 - （ OH ） D3 on premature infant lower than the children no premature. The levels of 25 - （OH） D3 in the children aged 0 -3 years are increased with month age, and reach maximum at 5 month, then it decrea- ses gradually.
出处
《中国妇幼保健》
CAS
北大核心
2013年第30期4982-4985,共4页
Maternal and Child Health Care of China
