摘要
本试验评价了新城疫(ND)疫苗和鸡痘(FP)疫苗免疫后对新城疫重组鸡痘病毒活疫苗(rFPV-ND-HN)免疫效力的影响。结果表明,用新城疫活疫苗和灭活疫苗进行基础免疫,不影响rFPV-ND-HN活疫苗的抗NDV免疫力的产生,但FP疫苗免疫后,再接种rFPV-ND-HN,免疫鸡既不能产生NDV HI抗体,也不能获得抗NDV强毒株攻击的保护力。
Protective immunity against Newcastle disease virus （NDV） induced by recombinant fowlpox virus expressing NDV HN gene （rFPV-ND-HN） in chickens previously vaccinated with ND or fowl pox （FP） vaccines was evaluated. The results demonstrated that vaccination with ND live or inactivated vaccine in chickens before inoculation with rFPV-ND-HN did not interfere with the immune protection against NDV infection. However, when the chickens were vaccinated with FP vaccine and then vaccinated with rFPV-ND-HN,the HI antibody and the protection against NDV in chickens were not induced.
出处
《中国家禽》
北大核心
2013年第19期19-21,共3页
China Poultry
基金
江苏省高技术研究计划(BG2007336)
江苏高校优势学科建设工程资助项目
关键词
新城疫
重组鸡痘病毒
疫苗
免疫应答
Newcastle disease
recombinant fowlpox virus
vaccine
immune response
