摘要
目的:对突托蜡梅(Chimonanthus grammatus M.C.Liu)叶的化学成分进行抑菌活性研究。方法:采用多种柱色谱技术进行分离,根据其理化性质和波谱数据鉴定化合物结构。结果:鉴定了9个化合物:蜡梅碱(1)、β-谷甾醇(2)、豆甾醇(3)、胡萝卜苷(4)、4-羟基-3((2E,6E)-3,7,11-三甲基十二烷-2,6,10-三烯)苯甲酸(5)、(E)-4-(4,8-二甲基壬-3,7-二烯)呋喃-2(5H)-酮(6)、邻苯二甲酸二异丁酯(7)、槲皮素(8)和东莨菪素(9);抑菌实验结果显示化合物5、6、7和9均对受试菌均有不同程度的抑菌活性。结论:化合物5、6、7和9均是首次在该属植物中分离得到,且均显示较好的抑菌活性。
Objective: To study antimicrobial activity and chemical constituents in the leaves of Chimonanthus grammatus M.C.Liu. Methods: Various chromatographic methods were adopted to isolate and purify the chemical constituents of C. grammatus leaves and their structures were identified and elucidated according to their physicochemical properties and spectral data. Results: Nine compounds were isolated and identified as chimonanthine (1), β-sitosterol (2), stigmasterol (3), daucosterol (4), prenylated 4-hydroxybenzoic acid (5), (E)-4-(4,8-dimethylnona-3,7-dienyl)furan-2(5H)-one (6), diisobutyl phthalate (7), quercetin (8) and scopoletin (9), respectively. Compounds 5, 6, 7 and 9 showed obvious antibiotic activity against indicator microorganisms tested. Conclusion: Compounds 5, 6, 7 and 9, having good antimicrobial activity, are isolated from plants of the genus Chimonanthus grammatus for the first time.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2013年第19期42-45,共4页
Food Science
基金
"十二五"国家科技支撑计划项目(2011BAC13B04)
国家自然科学基金项目(31260082)
"赣鄱英才555工程"领军人才计划项目
江西省自然科学基金项目(2009GZN0102
2010GZN0113)
江西省教育厅科技项目(GJJ10395
10702)
关键词
突托蜡梅叶
化学成分
抑菌活性
leavesofChimonanthusgrammatus
chemicalcomposition
antimicrobialactivity