嗅神经母细胞瘤影像学表现及文献复习

Imaging fings of esthesioneuroblastoma and literature review

目的:探讨嗅神经母细胞瘤病理学特点,提高诊断水平。方法:回顾性分析2例经手术病理证实的嗅神经母细胞瘤的临床、CT及病理学资料,并作文献复习。结果:嗅神经母细胞瘤在临床上可无特异性症状或因肿瘤压迫出现不典型症状。影像学表现为实性肿块,增强后实性呈不均匀明显强化。结论:嗅神经母细胞瘤诊断必须结合既往病史、临床症状,影像学对肿瘤的早期诊断及准确分期有重要价值,而确诊有赖于病理学与免疫组织化学诊断。

Objective：To explore the imaging tings and pathologic features of esthesioneuroblastoma, so as to improve its diagnostic accuracy. Methods：The clinical and imaing signs and pathologic data of 2 patients with pathologically proved esthe- sioneuroblastoma were analyzed and the relative literatures were reviewed. Results ： The patients with esthesioneuroblastoma were lacked of clinical symptoms or presented atypical symptoms due to the oppression of tumor. On magnetic resonance ima- ging and CT images the lesion of three cases was solid mass and the solid part of the mass was mild to apparent enhancement for two cases of the administration of contrast agent. Conclusion：The diagnosis of esthesioneuroblastoma should be combined with history, clinical appearance. The value of imaing diagnosis was limited, the final diagnosis of esthesioneuroblastoma was depended on the pathology and immunohistochemistry.