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高龄患者行颈动脉内膜切除术的安全性 被引量:1

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摘要 20世纪90年代,北美症状颈动脉内膜切除试验(North American Symptomatic Carotid Endarterectomy,NASCET)[1]、欧洲颈动脉手术试验(European Carotid Surgery Trial,ECST)[2]、无症状颈动脉粥样硬化研究(Asymptomatic Carotid Endarterectomy Trial,ACAS)[3]等3个前瞻性多中心临床试验已经证实了颈动脉内膜切除术(carotid endarterectomy,CEA)在治疗颈动脉粥样硬化方面的有效性和安全性,但是研究也发现不同年龄段患者,获益的程度也不相同,下面就本中心的研究数据进行分析,高龄患者与年轻患者相比,是否具有较好的安全性.
出处 《中华外科杂志》 CAS CSCD 北大核心 2013年第10期953-954,共2页 Chinese Journal of Surgery
基金 国家“十二五”科技支撑计划资助项目(2011BA108804)
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  • 1Beneficial effect of carotid endarterectomy in symptonmtic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med, 1991, 325 : 445 -453.
  • 2Randomlsed trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST). Lancet, 1998,351 : 1379-1387.
  • 3Moore WS, Kempczinski RF, Nelson JJ, et al. Recurrent carotid stenosis: results of the asymptomatic carotid atherosclerosis study. Stroke, 1998,29 : 2018-2025.
  • 4Brott TG, Halperin JL, Abbara S, et al. 2011 ASA/ACCF/AHA/ AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/ SVS guideline on the management of patients with extraeranial carotid and vertebral artery disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventionat Radiology, Society of Neurolnterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery. J Am Coll Cardiol, 2011 , 57 : 1002- 1044.
  • 5Khatri R, Chaudhry SA, Vazquez G, et al. Age differential between outcomes of carotid angioplasty and stent placement and carotid endarterectomy in general practice. J Vasc Surg,2012,55: 72-78.
  • 6Teso D, Edwards RE, Frattini JC, et al. Safety of carotid endarterectomy in 2, 443 elderly patients: lessons from nonagenarians--are we pushing the limit? . J Am Coil Surg,2005, 200:734-741.

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