强化抗血小板治疗短暂性脑缺血发作的疗效和安全性分析

Efficacy and Safety Analysis of TIA Treatment with Strengthen Anti-platelet Therapy

目的观察阿司匹林联合氯吡咯雷治疗短暂性脑缺血发作性的疗效性和安全性。方法将符合入选标准的71例患者随机分为联合治疗组(36例)和对照组阿司匹林组(35例)。两组均予基础治疗,对照组同时口服阿司匹林,治疗组在对照组基础上加服氯吡咯雷片,两组分别于治疗后14天检查凝血功能,并分别评定疗效。结果与阿司匹林组比较,强化抗血小板组可以显著改善患者神经功能的恢复情况和日常生活能力,并没有增加出血时间的发生率,减少卒中发生率。结论阿司匹林、氯吡咯雷联合抗血小板治疗TIA疗效显著,未见明显不良反应,可临床推广。

Objective Observing the efficacy and safety of the TIA treatment with Aspirin and Clopidogrel. Method Randomly grouping 71 patients into two groups： Combination therapy group（36 patients） and Contrast group （35 patients）. Contrast group with only Aspirin and the other with Aspirin and Ctopidogrel. After 14 days,check the coagulation and analyze. Result The recovery of Combination therapy group is much better than Contrast group in nerve function and activities of daily living, without increasing the incidence of bleeding time and the incidence of stroke. Conclusion The TIA treatment with Aspirin and Clopidogrel has sgnificant effect is safe,can be used in clinical treatment.