丹参注射液治疗妊娠高血压临床分析

Clinical analysis of salvia miltiorrhiza injection treating pregnancyinduced hypertension

目的探讨采用丹参注射液治疗临床妊娠高血压的效果及应用价值。方法回顾性分析240例妊娠高血压患者的一般资料,按照入院时间先后、对照的原则分为对照组和治疗组,各为120例。两组疗程均为7d,均采用常规的降压、扩容等治疗方法,对照组患者加用静脉给药硫酸镁进行治疗,治疗组则加用丹参注射液静脉滴注进行治疗。观察和比较两组临床治疗效果及不良反应的发生情况。结果治疗过程中,对照组出现14例不良反应,发生率为11.7%;治疗组出现4例不良反应,发生率为3.3%,两组比较,治疗组不良反应发生率明显低于对照组(x2=6.01,P<0.05);治疗结束后,对照组患者临床治疗总有效率为83.4%,治疗组患者临床治疗总有效率为93.4%,治疗组治疗效果明显优于对照组(x2=5.82,P<0.05)。结论临床采用丹参注射液治疗妊娠高血压效果显著,能够明显的改善孕妇的症状和体征,值得临床进一步研究推广应用。

Objective To study the effect and application value of Salvia Miltiorrhiza Injection for the treatment of clinical pregnancy-induced hypertension. Methods The general datas of 240 patients suffering from pregnancy- induced hypertension were retrospectively analysed, and 240 patients were divided into control group and treatment group according to the principle of being admitted to hospital successively and control.Each were 120 cases respectively.A course in both groups was 7 days.Two groups were given the conventional step-down,expansion treatment. Patients in control group were given intravenous magnesium sulfate treatment,and patients in treatment group were added with intravenous drip of Salvia Miltiorrhiza Injection for treatment. Clinical curative effect and adverse reaction of two groups were observed and analysed. Results Adverse reaction in control group was observed in 14 cases in the treatment process,and the incidence was ll.7%.Adverse reaction in treatment group was observed in 4 cases in the treatment process, and the incidence was 3.3%. The incidence of adverse reactions of treatment group was obviously lower than control group （x2= 6.01,P 〈 0.05）; The clinical total effective rate in control group after treatment was 83A%,and the clinical total effective rate was 93.4% in treatment group.The therapy effect of treatment group was better than control group（x2= 5.82,P 〈 0.05）. Conclusion The effect of clinical use of Salvia Miltiorrhiza Injection treating pregnancy-induced hypertension was significant,and Salvia Miltiorrhiza Injection can significantly improve the signs and symptoms of a pregnant woman,and it is worthy of clinical popularization and application for further research.