POEMS综合征合并糖尿病三例并文献复习

POEMS syndrome with diabetes mellitus： report of three cases and a review of the literature

汇报POEMS综合征合并糖尿病3例。3例患者均以周围神经病变为首发症状，同时患有糖尿病，初步诊断考虑糖尿病周围神经病变，但经过相关检查最终确诊为POEMS综合征。POEMS综合征是发病率较低的一种浆细胞克隆性病变，大多数患者以多发性周围神经病变首发起病。本文归纳了POEMS综合征多发性周围神经病变与糖尿病周围神经病变的鉴别诊断要点。

We reported three cases of POEMS syndrome with diabetes mellitus. All of the patients had the first symptom of peripheral neuropathy, as combined with diabetes mellitus. They were diagnosed initially as diabetic peripheral neuropathy. However, they were finally diagnosed as POEMS syndrome through related examinations. POEMS syndrome is a rare plasma cell clonal disorder and most of the patients come on with peripheral neuropathy. We summarize the features of differential diagnosis between polyneuropathy of the POEMS syndrome and diabetic peripheral neuropathy.