桑白皮化学成分研究

Study on the Chemical Constituents of Mori Cortex

目的:研究桑白皮的化学成分。方法:采用硅胶柱色谱对桑白皮经二氯甲烷-甲醇混合溶剂提取得到的浸膏进行分离纯化,根据理化性质和波谱数据分析鉴定化合物。结果:从桑白皮混合溶剂提取物中分离得到8个化合物,分别鉴定为:3-乙酰基-β-香树脂醇(1)、新生育酚(2)、α-香树精(3)、穿贝海绵甾醇(4)、桦木酸(5)、桑辛素O(6)、摩鲁新(7)、摩鲁新L(8)。结论:其中,化合物2、4为首次从该植物中分离得到。

Objective: To study the chemical constituents of Mori Cortex. Methods: The compounds from the dichloromethanemethanol extracts were isolated by the silica gel column chromatography,and their structures were identified by the spectral analysis and chemical evidence. Results: Eight compounds were obtained and their structures were identified as 3-acetyl-β-amyranol( 1),neotocopherol( 2),α-amyrin( 3),clionasterol( 4),betulinic acid( 5),moracin O( 6),morusin( 7) and morusignin L( 8). Conclusion:Componds 2 and 4 are obtained from this plant for the first time.