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血小板膜糖蛋白Ⅱb/Ⅲa受体拮抗剂的研究进展 被引量:1

Research Progress of Platelet Glycoprotein Ⅱb/Ⅲa Acceptor Antagonist
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摘要 血小板糖蛋白(GP)Ⅱb/Ⅲa受体是血小板聚集血栓形成的最终共同途径,(GP)Ⅱb/Ⅲa受体拮抗剂通过与受体结合抑制血小板凝集,从而抑制血栓形成,是一类高效和特异的抗血小板药物,越来越广泛地应用于择期经皮冠状动脉介入治疗(PCI)、非ST段抬高的急性冠脉综合征(NSTE-ACS)、ST段抬高心肌梗死(STEMI)等疾病。 Platelet glycoprotein(GP)Ⅱb /aⅢ receptor is the final common pathway of platelet aggregation in thrombus formation. GP Ⅱb /aⅢ receptor antagonist inhibits platelet aggregation by binding to the receptor and inhibits thrombosis, which is efficient and specific. GP Ⅱb /aⅢ receptor antagonist is more and more widely used in elective percutaneous coronary intervention (PCI), non-ST-segment elevation acute coronary syndrome (NSTE- ACS), ST segment elevation myocardial infarction (STEMI) and other diseases.
出处 《药品评价》 CAS 2013年第18期31-33,36,共4页 Drug Evaluation
基金 "抗心脑血管凝血 抗炎及抗病毒感染单抗药物的研制及应用"。国家高技术研究与发展计划(863计划)资助项目 编号:2006AA02A247
关键词 血小板糖蛋白 (GP)Ⅱb Ⅲa受体拮抗剂 血小板减少症 Platelet Glycoprotein GP IIb/IIIa Acceptor Antagonist Thrombocytopenia
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参考文献18

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