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温心通胶囊对冠心病患者及实验小鼠血清SOD活力和MDA水平的影响

Effects of "Wenxintong" Capsule on the Activity of SOD and Level of MDA in the serum of mice and patients with coronary heart disease
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摘要 目的:观察温心通胶囊抗氧化作用,进一步阐明该药物作用原理。方法:选择42例临床和3组(各30只)小白鼠,分别采用黄嘌呤氧化酶法、硫代巴比妥酸比色法作SOD及MDA实验。结果:临床总有效率80.96%;动物实验表明,治疗组与对照组有显著性差异(P<0.01)。结论:温心通胶囊能提高冠心病患者及实验小鼠血清SOD活力,降低MDA含量。 Objective: Observe the antioxidant effect of "Wenxintong" capsule , to furlher elucidate the mechanism of drug action . Methods: Choose 42 eases of clinical and 3 groups ( 30 in each ) in mice, respectively test SOD and MDA by using the method of xanthine oxidase and thiobarbituric acid eolorimetric method. Results: The total clinical effective rate is 80.96%, and animal experiments show that compared to the control group, the level of MDA decreased , activity of SOD elevated significantly in the treatment group ( P〈0.01 ) . Condusion:"Wenxintong" capsule can provide the antioxidant effect in mice and patients with coronary heart disease.
出处 《内蒙古中医药》 2013年第25期117-118,共2页 Inner Mongolia Journal of Traditional Chinese Medicine
关键词 温心通胶囊 冠心病相关因子 超氧化物歧化酶(SOD) 丙二醛(MDA) "Wenxintong" Capsule Coronary heart disease and related faetors SOD MDA
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